Association between a relative afferent pupillary defect using pupillography and inner retinal atrophy in optic nerve disease

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Association between a relative afferent pupillary defect using pupillography and inner retinal atrophy in optic nerve disease

PURPOSE The aim of this study was to compare the asymmetrical light reflex of the control subjects and patients with optic nerve disease and to evaluate the relationships among the relative afferent pupillary defect (RAPD), visual acuity (VA), central critical fusion frequency (CFF), ganglion cell complex thickness (GCCT), and circumpapillary retinal nerve fiber layer thickness (cpRNFLT) using ...

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Quantification of optic nerve axon loss associated with a relative afferent pupillary defect in the monkey.

OBJECTIVE To quantify the amount of optic nerve axonal loss associated with the presence of a mild relative afferent pupillary defect (RAPD) in an experimental monkey model. METHODS The right macula of 5 rhesus monkeys (Macaca mulatta) was treated with concentrically enlarging diode laser burns until an RAPD was detected using a transilluminator light and measured with neutral density filters...

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Retinal nerve fiber layer loss in glaucoma patients with a relative afferent pupillary defect.

PURPOSE To assess the amount of structural loss (retinal nerve fiber layer [RNFL] thickness loss, macular thickness [MT] and volume [MV] measured by optical coherence tomography [OCT]) and functional loss (visual acuity [VA], visual field mean deviation [MD], brightness sensitivity, and red perception) necessary for a relative afferent pupillary defect (RAPD) to manifest in patients with glauco...

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How to test for a relative afferent pupillary defect (RAPD)

Light source The ‘swinging light test’ is used to detect a relative afferent pupil defect (RAPD): a means of detecting differences between the two eyes in how they respond to a light shone in one eye at a time. The test can be very useful for detecting unilateral or asymmetrical disease of the retina or optic nerve (but only optic nerve disease that occurs in front of the optic chiasm). The phy...

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The afferent pupillary defect in acute optic neuritis.

Twenty-two patients with acute optic neuritis were studied by the techniques of infrared pupillometry and visual evoked responses (VER) to pattern reversal. A relative afferent pupillary defect was found in all cases and the magnitude of this defect was found to be related to the amplitude, but not to the latency, of the VER. During follow-up the afferent defect was found to remain persistently...

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ژورنال

عنوان ژورنال: Clinical Ophthalmology

سال: 2015

ISSN: 1177-5483

DOI: 10.2147/opth.s91278